{"product_id":"argireline-acetyl-hexapeptide-8","title":"Argireline, Acetyl Hexapeptide 8","description":"\u003cp\u003e\u003cstrong\u003eArgireline is Acetyl Hexapeptide-8, the peptide most associated with the look of expression lines — forehead creases, crow's feet, and the 11s between the brows. Blend it into your base at 2 - 10%.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis is a formulation ingredient, not a finished serum. Do not apply it undiluted.\u003c\/p\u003e\n\u003ch2\u003eWhat is in the bottle\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eINCI:\u003c\/strong\u003e Water, Acetyl Hexapeptide-8\u003c\/p\u003e\n\u003cp\u003eTwo ingredients. That is the whole list.\u003c\/p\u003e\n\u003cp\u003eClear liquid. Water-soluble. Fragrance-free, paraben-free. 0.5 oz blue glass dropper bottle.\u003c\/p\u003e\n\u003ch2\u003eThe science: Acetyl Hexapeptide-8 and the SNARE complex\u003c\/h2\u003e\n\u003cp\u003eArgireline is a six-amino-acid sequence, first introduced in 2001 and one of the most studied cosmetic peptides in use.\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 0.875rem;\"\u003eThe published research centers on the \u003c\/span\u003e\u003cstrong style=\"font-size: 0.875rem;\"\u003eSNARE complex\u003c\/strong\u003e\u003cspan style=\"font-size: 0.875rem;\"\u003e — the protein assembly that mediates signaling at the neuromuscular junction.\u003c\/span\u003e Acetyl Hexapeptide-8 has been studied for its interaction with SNARE complex formation, which is why it is grouped with the expression-line peptides rather than the collagen-support ones.\u003c\/p\u003e\n\u003cp\u003eThe supplier's efficacy work reports improved appearance of fine lines at a 2% concentration, with measured reductions in wrinkle depth and volume.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eThese findings are the manufacturer's, from their efficacy dossier, and we reproduce them here under our license agreement. They describe testing of the raw material, not of a finished product you blend at home.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003eHow much to add\u003c\/h2\u003e\n\u003cp\u003eRecommended usage rate is 2 to 10%. Using our house rate of 9 drops per 1% per fluid ounce:\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eConcentration\u003c\/th\u003e\n\u003cth\u003eInto 1 oz\u003c\/th\u003e\n\u003cth\u003eInto 2 oz\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e2%\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e18 drops · 0.6 g\u003c\/td\u003e\n\u003ctd\u003e36 drops · 1.2 g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e5%\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e45 drops · 1.5 g\u003c\/td\u003e\n\u003ctd\u003e90 drops · 3.0 g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e10%\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e90 drops · 3.0 g\u003c\/td\u003e\n\u003ctd\u003e180 drops · 6.0 g\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eSee the \u003ca href=\"\/en-de\/pages\/product-instructions-for-serum-boosters\"\u003eserum booster chart for full conversions\u003c\/a\u003e. Every order includes an instruction guide and chart. \u003c\/p\u003e\n\u003ch2\u003eHow to use it\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eChoose a water-based serum, gel, lotion, or cream. \u003ca href=\"\/en-de\/products\/hyaluronic-acid-serum\"\u003eHyaluronic acid serum\u003c\/a\u003e is the usual base.\u003c\/li\u003e\n\u003cli\u003eAdd the drops for the percentage you want.\u003c\/li\u003e\n\u003cli\u003eCap and shake well.\u003c\/li\u003e\n\u003cli\u003eRefrigerate what you are not using.\u003c\/li\u003e\n\u003cli\u003eApply the finished blend morning and night to the forehead, around the eyes, and the lip area.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003eWhat it is for\u003c\/h2\u003e\n\u003cp\u003eArgireline is formulated for the lines that come from movement rather than sun or slack — the ones that deepen because your face makes the same shapes every day.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eForehead creases\u003c\/li\u003e\n\u003cli\u003eThe 11s between the brows\u003c\/li\u003e\n\u003cli\u003eCrow's feet at the outer corners of the eyes\u003c\/li\u003e\n\u003cli\u003eFine lines around the mouth\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor firmness across the whole face rather than specific lines, \u003ca href=\"\/en-de\/collections\/matrixyl\"\u003eMatrixyl 3000\u003c\/a\u003e is the one to reach for instead. They layer well together.\u003c\/p\u003e\n\u003ch2\u003eWhy buy it raw\u003c\/h2\u003e\n\u003cp\u003eFinished products naming this ingredient rarely tell you how much is in them, and it is usually less than you would choose. Blend it yourself and the number is yours — because you counted the drops in.\u003c\/p\u003e\n\u003cp\u003eOne 0.5 oz bottle blends several ounces of finished serum, depending on the percentage you pick.\u003c\/p\u003e\n\u003ch2\u003eBlending with other peptides\u003c\/h2\u003e\n\u003cp\u003eArgireline layers with \u003ca href=\"\/en-de\/collections\/snap-8\"\u003eSnap-8\u003c\/a\u003e, \u003ca href=\"\/en-de\/products\/syn-ake\"\u003eSyn-Ake,\u003c\/a\u003e and \u003ca href=\"\/en-de\/products\/inyline-solution\"\u003eInyline\u003c\/a\u003e. Each works on the look of expression lines through a different route, so combining them doesn't double up on the same thing. Keep the combined total sensible — the base still has to be mostly base.\u003c\/p\u003e\n\u003cp\u003ePrefer liposomal delivery and a lower use rate? See \u003ca href=\"\/en-de\/products\/argireline-amplified-peptide\"\u003eArgireline Amplified\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eStorage\u003c\/h2\u003e\n\u003cp\u003eRefrigerate on arrival. The blue glass keeps light out.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor external use only. Cosmetic grade. Do not apply undiluted to skin. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eArgireline is a registered trademark of Lipotec S.A.U., used under license.\u003c\/em\u003e\u003c\/p\u003e","brand":"Skin Perfection","offers":[{"title":"Default Title","offer_id":31588265197625,"sku":"SPO-Argireline-.5oz","price":34.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0069\/7719\/1993\/files\/acetyl-hexapeptide-argireline-peptide.jpg?v=1762819316","url":"https:\/\/nituralorganicskincare.com\/en-de\/products\/argireline-acetyl-hexapeptide-8","provider":"Skin Perfection Natural and Organic Skin Care","version":"1.0","type":"link"}